Iicapsules ezingenanto, njengomphathi oqhelekileyo wamachiza, i-nutraceuticals, okanye iziqulatho zokutya, ziza kwiindidi ezahlukahlukeneyo ezityebileyo. Zihlelwa ikakhulu ngokusekwe kwimithombo yendalo ekrwada, iimpawu zesakhiwo, kunye nokusetyenziswa okusebenzayo. Ukuqonda iimpawu zeentlobo ezahlukeneyo ze-capsule ezingenanto kubaluleke kakhulu kuphando lweziyobisi kunye nophuhliso, imveliso, kunye nezicelo zeklinikhi.
Ihlelwa ngokomthombo wemathiriyeli ekrwada, ezona ntlobo zisisiseko zee-capsules ezingenanto ziwela kwiindidi ezimbini ezinkulu: isilwanyana-esekwe kunye nesityalo{1}esekwe. Izilwanyana -iikhepsuli ezisekwe kwisilwanyana zimelwe yigelatin capsules, ezinemathiriyeli ekrwada zisuka ikakhulu kwi-hydrolyzed collagen yesikhumba sehagu, isikhumba senkomo, okanye ithambo. Banikezela ngeenzuzo ezifana nembali ende yokusetyenziswa, ixabiso eliphantsi, ukubunjwa okulungileyo, kunye namazinga okuchithwa okuzinzile, okwenza kube yintlobo ye-capsule esetyenziswa kakhulu namhlanje. Nangona kunjalo, ngenxa yemvelaphi yazo yezilwanyana kunye neengqwalasela ezinxulumene neenkolelo zonqulo kunye nemifuno, ukusetyenziswa kwazo kuxhomekeke kwimiqathango ethile. Izityalo -i-capsules ezisekelwe kwizityalo ziye zayeyona ndlela ibalulekileyo, ingakumbi i-HPMC capsules kunye ne-pululan capsules. Iipilisi ze-HPMC, ezenziwe kwi-cellulose yesityalo, zifanelekile kwimifuno kwaye zibonisa uzinzo olungcono phantsi kobushushu obuphezulu kunye nokufuma. Iicapsules zePullulan, eziveliswe ngokuvutshelwa kwe-microbial, zibonisa ukunyanzeliswa kwe-oksijini ephantsi kunye neempawu eziqinileyo zokutywinwa, ezinikezela ukhuseleko oluphuculweyo lweziqulatho.
Ngokusekwe kwiimpawu zolwakhiwo, iicapsules ezingenanto zinokohlulwa zibe yi-gelatin capsules, i-enteric{0}}egqunywe iicapsules ezingenanto, kunye ne-halal capsules. I-gelatin eqhelekileyo i-capsules engenanto ichithakala kwaye ikhulule imixholo yazo kwijusi yesisu, ibenze bafaneleke kumachiza amaninzi afakwe kwi-gastrointestinal tract. I-Enteric -i-capsules ezigqunyiweyo, nangona kunjalo, zisebenzisa itekhnoloji yokugquma ezikhethekileyo (ezifana ne-acrylic resin materials) ukunqanda ukunyibilika kwindawo eneasidi yesisu, ezivumela ukuba ziqhekeke kuphela kwindawo yealkaline yamathumbu. Oku kuthintela ngokufanelekileyo ukucaphuka kwi-gastric mucosa okanye ikhusela amacandelo angenakwenziwa lula nge-asidi yesisu, njengeprobiotics kunye ne-enzymes ethile. Ukongeza, ngokusekwe kwinkangeleko kunye neendlela zokuvala, ii-capsules zinokuhlelwa njenge-transparent, semi{6}}transparent, okanye i-opaque, kwaye njengesiqhelo{7}}isitshixo okanye ukhuseleko{8}}lokhuseleko lwe-capsules, kunye neyokugqibela ikhusela ngokufanelekileyo ukuvulwa ngengozi ngexesha lokuthutha kunye nokugcinwa.
Ihlelwe ngumsebenzi kunye nokusetyenziswa, ukongeza kwii-capsules eziqhelekileyo zamachiza, kukwakho ii-capsules ezongezelelweyo zezempilo kunye nee-capsules ezongezelelweyo zokutya. Ezi capsules zineemfuno eziphezulu zokhuseleko kunye nococeko lwemathiriyeli ekrwada kwaye kufuneka zihambelane nemigangatho yokutya ehambelanayo-nomgangatho. Ngenkqubela phambili yetekhnoloji, iicapsules ezisebenzayo ezinjengokugcinwa-iikhepsuli zokukhutshwa kunye nesayithi{4}}iikhepsuli zokukhupha ezikhethekileyo nazo ziyavela. Ngokulungelelanisa izinto zegobolondo okanye isakhiwo, ezi capsules zenza ukuba kukhululwe iziyobisi kwiindawo ezithile okanye kumazinga alawulwayo, ukuphucula ngakumbi iziphumo zonyango.
Ngamafutshane, ulwahlulo lwee-capsules ezingenanto zininzi -zobukhulu kwaye zinenkcukacha. Ukusuka kwiicapsules zegelatin zesintu ukuya kwizityalo ezisahlumayo{2}ezisekelwe, kunye nokusuka kwiintlobo eziqhelekileyo zegastro{3}}ezinyibilikayo ukuya kwiintlobo ezikhethekileyo ze-enteric, uhlobo ngalunye lusebenzisa iinzuzo zalo ezizodwa ukuhlangabezana neempawu zamachiza ahlukeneyo, iimfuno zesigulana, kunye neemfuno zenkqubo yokuvelisa, ukubonelela ngeendlela ezahlukeneyo zokuthwala amayeza kunye nempilo yanamhlanje. Ukuba kukho naziphi na iimfuno kwii-capsules ezingenanto, wamkelekile ukuba uqhagamshelane ne-KornnacCaps.
