NjengeeMpahla zamachiza, umgangatho wee-capsules ezingenanto zichaza ngokuthe ngqo ukhuseleko, ukusebenza, kunye nokuzinza kwemveliso yokugqibela yamayeza. Ukuba la maqokobhe e-capsule abonakala elula aneziphene ngaphambi kokuba azaliswe ngamayeza, anokuba yingozi enkulu efihlakeleyo kumgangatho wamachiza. Ezi ziphene aziveli kuphela ekuphambukeni kwenkqubo ngexesha lemveliso kodwa zinxulumene ngokusondeleyo nolawulo olungafanelekanga lokusingqongileyo ngexesha lokugcinwa kunye nokuthutha. Zinokwahlulwa ngokubanzi zibe ziindidi ezintathu eziphambili: ezomzimba, iikhemikhali, kunye nebhayoloji.
Iziphene zomzimba lolona hlobo lunengqiqo kwaye luqhelekileyo. Eyokuqala yi-Fragility okanye i-Brittleness. Iqokobhe le-capsule elifanelekileyo kufuneka libe ne-elasticity ephakathi kunye nokuqina. I-capsule ye-brittle ixhomekeke kakhulu ekuqhekekeni ngexesha lokuthutha okanye inkqubo yokuzalisa, ekhokelela ekuvuzeni kweziyobisi kunye ne-dosing engafanelekanga. Okulandelayo kukutyeba okungalinganiyo okanye iiBhabhula zoMoya, ezinokuchaphazela izinga lokuchithwa kwe-capsule, okunokubangela ukuba ichiza likhutshwe ngokukhawuleza okanye ngokucothayo emzimbeni, ngaloo ndlela libe nefuthe kwisiphumo salo sonyango. Ngaphaya koko, iDimensional Deviation ngumba omkhulu wemveliso. Ukuba imilinganiselo ye-cap kunye nomzimba ayihambelani ngokufanelekileyo, kuya kubangela ukutywinwa okungahambi kakuhle, okubangela ukuba bahlukane ngokulula ngexesha lokugcinwa kunye nokubeka ichiza kwindawo engqongileyo, okukhokelela ekuthotyweni. Ukungafezeki komphezulu okunje ngeMikrwelo, amabala, okanye ukuPhuculwa kombala ayiyomiba nje yobuhle; ziyakwazi nokuba yimiqondiso yezinto ezingcolileyo okanye ukungcola ngexesha lenkqubo yokuvelisa.
Iziphene zemichiza zifihlakele ngakumbi kodwa ziyingozi kakhulu. Undoqo womba ulele kumgangatho wegelatin. Ukuba imathiriyeli ekrwada ekumgangatho ophantsi, njenge{2}}engamayeza{3}}ibakala lejelatin, iyasetyenziswa, okanye ukuba izinto ezinobungozi zithe zaziswa ngexesha lemveliso, amaqokobhe e capsule angaqulatha amanqanaba agqithisileyo esinyithi esinzima (njengechromium), intsalela yetitanium dioxide, okanye izinyibilikisi ezinobungozi eziphilayo. Ezi zinto zemichiza zinokuqokelelana kumzimba womntu ngokuhamba kwexesha, zibangele ubungozi obunokubakho kumalungu anjengesibindi kunye nezintso. Isehlo seToxic Capsule esothusa isizwe kwiminyaka eliqela eyadlulayo yaba sisiphumo esithe ngqo sokusebenzisa igelatin yamashishini, ekhokelele kumanqanaba agqithisileyo echromium yentsimbi enzima kwaye yabeka isoyikiso esikhulu kwimpilo yoluntu. Ukongezelela, ukuba ixabiso le-pH legobolondo le-capsule alikho kumgangatho, linokusabela kunye neziyobisi ezithile ze-alkaline okanye ezine-acidic, ezibangela ukuba zithobe okanye zivelise izinto ezinobungozi.
Iziphene zebhayoloji zibhekisa ikakhulu kungcoliseko lwentsholongwane. Utyebile kwiprotheyini kunye nokufuma, ii-capsules ezingenanto ziyindawo efanelekileyo yokukhula kwe-microbial. Ukuba ucoceko lwemeko-bume yemveliso lukumgangatho ophantsi okanye ukuba indawo yokugcina ifumile kakhulu, amaqokobhe e-capsule anokosuleleka ngokulula ziibhaktheriya, ukungunda, okanye ii-microorganisms ze-pathogenic. Iicapsules ezingenanto ezosulelwe ziintsholongwane azilonakalisi nje kuphela ichiza, ezinokubangela usulelo lwamathumbu okanye ukuchasana nezigulana, kodwa i-metabolic byproducts yazo (efana ne-mycotoxins) zikwanomhlaza kakhulu. Ke ngoko, ukwenza iimvavanyo ezingqongqo ze-microbial kwi-capsules ezingenanto yinxalenye eyimfuneko yolawulo lomgangatho.
Ukuqukumbela, iziphene zee-capsules ezingenanto zikude nokuba yinto elula yokubonakala kakubi. Ukusuka kwingqibelelo yomzimba kunye nokucoceka kweekhemikhali ukuya kukhuseleko lwebhayoloji, nakuphi na ukongamela kuyo nayiphi na kwezi ndawo kunokutyala umngcipheko wokhuseleko ofihliweyo. Ngenxa yoko, iinkampani zamachiza kufuneka ziqhube uphicotho olungqongqo kunye novavanyo xa zikhetha ababoneleli be-capsule abangenanto, ngelixa ii-arhente ezilawulayo kufuneka ziqhubeke ziqinisa ukugada ukuze ziqinisekise ukuba olu luhlu luncinci lweMpahla lusebenza ngokwenene njengomqobo oqinileyo okhusela impilo yesigulane, kunokuba i-Time Bomb enokubakho yeengozi ezifihliweyo. Ukuba kukho nayiphi na eminye imibuzo malunga neecapsules ezingenanto, wamkelekile ukuba uqhagamshelane neKornnacCaps.
