Kwiinkalo zamayeza kunye nezongezo zempilo,engenanto iipilisi zegelatinbadlala indima ebaluleke kakhulu. La maqokobhe e-capsule -amacandelo amabini, enziwe ngegelatin yamayeza asulungekileyo, awasombululi kuphela ingxaki yokuthatha amayeza anzima kwizigulana, kodwa adlala indima ephambili ekukhuseleni ichiza kunye nokuphucula incasa. Ngophuhliso olukhawulezayo lweshishini lamayeza kunye nendlela eyandayo yokuguga kwabantu, imfuno yentengiso yeecapsules zegelatin engenanto iyaqhubeka nokukhula, kwaye iimeko zokusetyenziswa kwazo ziya zisiya zihluka. Eli nqaku liza nzulu ukuba zeziphi iipilisi zegelatin ezingenanto ezisetyenziselwa? kwaye utyhile indima ebalulekileyo emva kwale capsule encinci.
Ukhuseleko lweziyobisi kunye nomsebenzi oZinzileyo-wokuKhupha
Umsebenzi oyintloko we-gelatin capsules kukukhusela ichiza kwimpembelelo yendawo yangaphandle. Iqokobhe le-capsule lisebenza njengesithintelo, lithintela ngokufanelekileyo iyeza ekudibaneni ngqo nomoya kunye nokufuma, ngaloo ndlela kuthintelwa ukufunxwa kokufuma ngamasuntswana echiza, okunokukhokelela ekwehleni kokusebenza kwechiza. Amachiza amaninzi akakuva ukukhanya, ukufuma nomoya. Iipilisi zeGelatin zibonelela ngemeko ezinzileyo eqinisekisa ukuzinza kweziyobisi ngexesha lokugcinwa kunye nokuthutha, ngaloo ndlela iqinisekisa ukusebenza kweyeza. Kwizigulane ezinezifo ezingapheliyo ekufuneka zithathe iyeza ixesha elide, ukugcinwa okuzinzileyo{4}}kokukhutshwa kwe-gelatin capsules engenanto kubaluleke kakhulu. Ingayilwa njengohlobo oluzinzileyo-lokukhutshwa okanye olulawulwayo{7}}, oluvumela ichiza ukuba likhutshwe kancinci emzimbeni, longeze ixesha lesenzo, licuthe inani leedosi, kunye nokuphucula isiphumo sonyango.
Ukongeza, i-gelatin i-capsules engenanto inokunciphisa ngokufanelekileyo ukucaphuka kweyeza kwi-gastrointestinal tract. Amanye amachiza anokubangela iziphumo ezibi xa edlula kummizo kunye nomlomo, njengezilonda zomlomo. Ukusebenzisa i-gelatin capsules ukugquma iyeza kunokunciphisa ukucaphuka ngokuthe ngqo kwechiza emlonyeni kunye nommizo, ukuphucula intuthuzelo yezigulane xa uthatha iyeza. Amachiza ekufuneka athathwe kwisisu esingenalutho, i-capsules inokuthintela ukuba iyeza linganyibiliki ngaphambi kwexesha kwi-asidi yesisu, ukuphucula ukufumaneka kweyeza.
Ukuphucula iNcasa kunye nokuPhucula ukuThotyelwa kweMichiza
Amachiza amaninzi anencasa ekrakrayo okanye anevumba elibi, nto leyo eyenza kube nzima ngezigulana ukuwamkela. Iipilisi zegelatin ezingenanto ziyisombulula ngokuchanekileyo le ngxaki. Iipilisi ziyakwazi ukufihla incasa ekrakra okanye ivumba elibi lamachiza, ukuphucula incasa kunye nokwenza kube lula ukuba izigulane zamkele. Ngokukodwa kubantwana kunye nabantu abadala, ii-capsules zincinci ngobukhulu kwaye zilula ukuginya, zikhuthaza kakhulu ukuthotyelwa kweyeza. Ezinye izongezo zempilo ezingemnandanga{4}}ezinje nge-oyile yentlanzi kunye neeprobiotics zisoloko zipakishwa kwiipilisi zegelatin, ezivumela abathengi ukuba bazithathe ngaphandle komthwalo ngokwasengqondweni.
Iinkcazo zee-capsules zihlukeneyo, kwaye ubungakanani obufanelekileyo be-capsule bunokukhethwa ngokusekelwe kumthamo kunye nohlobo lweyeza. Amashishini afana ne-Hubei Kornnac Pharmaceutical Co., Ltd. (KornnacCaps) avelisa iinkcukacha ezahlukeneyo zee-capsules zegelatin ezingenanto, ezihlangabezana neemfuno zokupakisha zamachiza ahlukeneyo. Ukongeza, isicatshulwa, iimpawu zokuthengisa kunye neepatheni zinokuprintwa kwii-capsules, zibonise inkangeleko ekhethekileyo eyenziwe ngokwezifiso. Oku akuncedisi ukuchongwa kuphela kodwa konyusa ukuqondwa kwemveliso.
Ukwandiswa koBomi beShelf kunye nokuQondwa kweeFom zeDosi eKhethekileyo
I-Gelatin capsules engenanto idlala indima ebalulekileyo ekwandiseni ubomi beshelufu yamachiza. Xa amachiza egcinwe kwindawo evaliweyo kunye neoksijini{1}ekhululekileyo, anokunqanda nayiphi na impembelelo ekusebenzeni kwawo kwaye agcine ukusebenza kwawo ixesha elide. Emva kokuba ichiza lifakwe kwi-capsule ye-gelatin, kuthatha ixesha elithile ukuba ijusi yesisu idle i-gelatin kumphezulu weyeza. Le nkqubo ibambezela ngokufanelekileyo uqhagamshelwano phakathi kwechiza kunye nenkqubo yokugaya, ukuthintela ukukhululwa kwangaphambili kweyeza kunye nokuphepha ukucaphukisa kwinkqubo yokugaya.
Ukuqulunqwa kwe-capsule kwakhona kunika amathuba amaninzi amachiza. Iyakwazi ukuthwala umgubo ohlukeneyo, ulwelo, isiqingatha -eziqinileyo kunye neetafile, kwaye ifaneleke ngakumbi loo machiza ekunzima ukuba enziwe abe ngamacwecwe. Amanye amachiza akhethekileyo adinga indawo ethile ye-pH ukuze akhululwe. Iipilisi zeGelatin zinokuthi ziyilwe ngeepropati ezahlukeneyo zokuchithwa njengeegobolondo zokuphumeza imisebenzi ekhethekileyo efana ne-enteric okanye i-gastric dissolution. Kwinkalo yezongezo zezempilo, iipilisi zegelatin zisebenza ngakumbi. Iivithamini ezahlukeneyo, iiminerali, kunye nomgubo waseTshayina womgubo uhlala ukwimo ye-capsule, okwenza kube lula ukuba abathengi baphathe kwaye bathathe.
Nangonaii-capsules ze-gelatin ezingenantozincinci ngobukhulu, zithwala uxanduva oluninzi olunjengokuqinisekisa ukusebenza kweyeza, ukuphucula incasa, kunye nokuphucula ukuthotyelwa kwesigulane. Asiyondlela nje elula yokupakishwa kweziyobisi; ikwayinxalenye ebalulekileyo yophando lwamachiza kunye namava amayeza esigulane. Ukusuka ekukhuseleni iyeza ukuya ekuphuculeni incasa, ukusuka ekwandiseni ubomi beshelufu ukuya ekufikeleleni kwifomu yedosi ekhethekileyo, iicapsules zegelatin zidlala indima engenakuthathelwa indawo kumacandelo amayeza kunye nezongezo zempilo. Ngokumisela umgangatho weshishini kunye nokuqhubela phambili kweteknoloji, le capsule encinci iya kuqhubeka nokwenza igalelo elikhulu kwisizathu sempilo yabantu. Kubathengi, ukuqonda imisebenzi kunye nemiphumo yee-capsules ze-gelatin ezingenanto zibanceda baqonde ngcono iimpawu zamayeza kunye nezongezo zezempilo, ukuphucula ukuthotyelwa kwamayeza, kwaye ekugqibeleni bazuze iziphumo ezingcono zempilo.
