Njengendlela eqhelekileyo yokupakisha amayeza kunye neemveliso zempilo, ukwakhiwa kweekhemikhali kunye neempawu ze-gelatin capsules kubalulekile kumgangatho kunye nokhuseleko. Ukuqonda ukubekwa kweekhemikhali ze-gelatin capsules kuya kunceda abathumeli ngaphandle kunye nabathengi bamanye amazwe bavavanya ngcono imigangatho yemveliso.
Elona candelo liphambili le-gelatin ye-gelatin, indalo ephezulu - protein ye-molecular eyenziwe yi-hydrolysis ye-hydrolysim ye-cessgen ye-cessgen yesilwanyana. I-collagen ihlala isuselwa kulusu kunye namathambo ezilwanyana ezinjengeenkomo kunye neehagu, kwaye i-getitin ikhutshwe emva kwe-Acid okanye iAlkali. IGelatiny ngokwayo ingumxube, ubukhulu becala iqulethe i-Amino Acids njenge-Glycine, i-proline, kunye ne-Hydroxyproline, enika ifilimu ye-getratin, inika ifilimu elungileyo -
Ukongeza kwi-gelatin, iicaphule zinokuqulatha iziqu ezincinane zokuphucula intsebenzo yazo okanye zilungelelane neemfuno ezithile. Umzekelo, i-glycerol okanye i-shorbil ihlala isetyenziswa njengabaphangisi ukwandisa ukuguquguquka kweecaphule kwaye kuthintele ukuqhekeka kwe-Brittle; I-titanium diokside inokusetyenziswa njengeSctricreen ukuvelisa iicaphue ze-opaque; Ukongeza, isixa esincinci sezinto ezilondolozo okanye izinto ezinokuthi zongezwe ukuze zifezekise iimfuno zeemveliso ezahlukeneyo. Kufanelekile ukuba uqaphele ukuba abo bane-gelatin capsules kufuneka bathobele imigangatho yokhuseleko lokutya, ukuqinisekisa ukhuseleko lwabo kumayeza nakwimveliso yezempilo.
Kwiminyaka yakutshanje, imfuno yesityalo - i-capsules esekwe ngokuthe ngcembe iyenyuka ngokuthe ngcembe, ngakumbi iimarike ezijolise kubathengi bezityalo nezityalo zenkolo okanye izithintelo zokutya. Izityalo ezityalotile zihlala zisebenzisa i-hydroxlypropyl methylcelsele (i-HPMC) njengesithako esiphambili, esineepropathi zeekhemikhali ezahlukeneyo ukusuka kwiGelatin kodwa inokubonelela ngokusebenza ngokuzinzileyo. Nangona kunjalo, i-capin yemveli ye-gelatin iselukhetho oluqhelekileyo kwimarike ngenxa yenkqubo yabo yeqonga kunye nesicelo sawo ngokubanzi.
Kurhwebo lwamanye amazwe, imigangatho esemgangathweni ye-gelatin ye-gelatini idla ngokubhekisa kumalungiselelo e-Chinese pharmacopoeia okanye i-pharmacopoeias ye-pharmacopoeiaias (efana ne-USP, i-EP), kwaye ineemfuno ezingqongqo kwimpawu ezinzima kunye nemida ye-microbial. Iinkampani ezithumela ngaphandle kufuneka ziqinisekise ukuba iimveliso zabo ziyahambelana nemigaqo yemakethi ekujoliswe kuyo, ngakumbi kwimimandla efana ne-EU kunye ne-United States enezithintelo ezingqongqo kunye nezithintelo ezingcolisayo.
Ukuqulunqwa kwekhemikhali ye-gelatin capsules kuchaphazela ngokuthe ngqo iipropathi zabo kunye nokwenza isicelo. Ukuqonda ezi ziseko ziya kunceda iinkampani zikhethe iimveliso ezifanelekileyo kwimakethi yamanye amazwe yokuhlangabezana neemfuno ezahlukeneyo.
